Wp/nth/Alzheimer's ill

From Incubator Plus 2.0
< Wp‎ | nth
Drawin comparin a normal brain (left) an the brian ov a body wiv Alzheimer's (reet)

Alzheimer's disease (AD), whiles referred te as nobbut Alzheimer's an â, is a chronic neurodegenerative disease at usually starts slaw an warsens ower time.[1][2] It is the cause o 60–70% of cases o dementia.[1][2] The maist common early symptom is difficulty wi rememberin recent events (short-term memory loss).[1] As the disease gans on, symptoms can include problems wi language, disorientation (includin gettin lost easy), muid swings, loss o motivation, difficulty wi sel care, an behavioural issues.[1][2] As a body's condition gets warse, they often withdraw frae their family an society.[1] Ower time, bodily functions is lost, ultimately leadin te deeth.[3] Tho the speed o progression can vary, the typical life expectancy follaïn diagnosis is aboot three te nine year.[4][5]

Cause, diagnosis and prevention[edit]

The cause ov Alzheimer's disease isn't weel understuid.[1] Aboot 70% o the risk is believed te be genetic, wi mony genes ordinarily involved.[6] Uther risk factors includes a history o heed injuries, depression, or hypertension.[1] The disease process is associated wi plaques an tangles i the brain.[6] A probable diagnosis is based on a family history o the illness an cognitive testin wi medical imagin an bluid tests te rule oot uther possible causes.[7] Initial symptoms is often mistaen for normal agein.[1] Examination o the brain tissue is needed for a definite diagnosis.[6] Mental an physical exercise, an avoidin obesity might decrease the risk o AD; hooaniver, the evidence te support these recommendations isn't strang.[6][8] There isn't ony medications or supplements at hez been shown te decrease the risk.[9]

Ne treatments stops or revarses its progression, tho some may temporarily improve symptoms.[2] Affected folk increasingly relies on uthers for assistance, often placin a burden on the caregiver; the pressurs can include social, psychological, physical, an economic elements.[10] Exercise programmes may be beneficial wi respect te daily an can mebbe improve ootcomes.[11] Behavioural problems or psychosis acause o dementia is often treated wi antipsychotics, but this isn't usually recommended, as there isn't mickle benefit an an increased risk o early deeth.[12][13]

I 2015, there was aboot 29.8 million fowk warldwide wi AD.[2][14] It maist often begins i folk at's ower 65 year aud, tho 4% te 5% o cases is early-onset Alzheimer's at begins afore this.[15] It affects aboot 6% o folk ower 65.[1] In 2015, dementia resultit in aboot 1.9 million daiths.[16] It wis furst described biv, an later named efter, German psychiatrist an pathologist Alois Alzheimer i 1906.[17] In developed countriess, AD is ane o the maist financially costly diseases.[18][19]

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 "Alzheimer's disease" (February 2009). BMJ 338: b158. doi:10.1136/bmj.b158. PMID 19196745. 
  2. ↑ 2.0 2.1 2.2 2.3 2.4 "Dementia Fact sheet". World Health Organization (12 December 2017).
  3. ↑ "About Alzheimer's Disease: Symptoms". National Institute on Aging.
  4. ↑ "Alzheimer's disease" (January 2010). The New England Journal of Medicine 362 (4): 329–44. doi:10.1056/NEJMra0909142. PMID 20107219. 
  5. ↑ "Survival in dementia and predictors of mortality: a review" (November 2013). International Journal of Geriatric Psychiatry 28 (11): 1109–24. doi:10.1002/gps.3946. PMID 23526458. 
  6. ↑ 6.0 6.1 6.2 6.3 "Alzheimer's disease" (March 2011). Lancet 377 (9770): 1019–31. doi:10.1016/S0140-6736(10)61349-9. PMID 21371747. 
  7. ↑ "Dementia diagnosis and assessment". National Institute for Health and Care Excellence (NICE).
  8. ↑ "So, What Can You Do?" (in en). National Institute on Aging (29 July 2016). Template:Webarchive
  9. ↑ Template:Vcite journal
  10. ↑ Template:Vcite journal
  11. ↑ "Exercise programs for people with dementia" (April 2015). The Cochrane Database of Systematic Reviews 132 (4): 195–96. doi:10.1002/14651858.CD006489.pub4. PMID 25874613. 
  12. ↑ National Institute for Health and Clinical Excellence. "Low-dose antipsychotics in people with dementia". National Institute for Health and Care Excellence (NICE). Template:Webarchive
  13. ↑ "Information for Healthcare Professionals: Conventional Antipsychotics". US Food and Drug Administration (16 June 2008).
  14. ↑ "Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015" (October 2016). Lancet 388 (10053): 1545–602. doi:10.1016/S0140-6736(16)31678-6. PMID 27733282. 
  15. ↑ "Early-onset Alzheimer's disease: nonamnestic subtypes and type 2 AD" (November 2012). Archives of Medical Research 43 (8): 677–85. doi:10.1016/j.arcmed.2012.11.009. PMID 23178565. 
  16. ↑ "Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015" (October 2016). Lancet 388 (10053): 1459–544. doi:10.1016/S0140-6736(16)31012-1. PMID 27733281. 
  17. ↑ Template:Vcite journal
  18. ↑ Template:Vcite journal
  19. ↑ Template:Vcite journal
Retrieved from "https://incubator.miraheze.org/wiki/Wp/nth/Alzheimer%27s_ill?oldid=26448"