Wp/nth/Alzheimer's ill

Alzheimer's disease or Alzheimer's ill is a neurodegenerative disease that usually starts slaw and progressively warsens. It is the cause of 60–70% o cases o dementia. The myest common early symptom is difficulty wi remembering recent events. As the disease advances, symptoms can include problems wi language, disorientation (includin getting lost easy), mood swings, loss o motivation, sel-neglect, and behavioral issues. As a parson's condition declines, they often withdraw frae their family and society. Gradually, bodily functions is lost, ultimately leadin te deeth. Though the speed o progression can vary, the typical life expectancy follaïn diagnosis is three te nine years.

The cause of Alzheimer's disease is poorly understuid. There's mony environmental and genetic risk factors associated wiv its development. The strangest genetic risk factor is frev an allele of APOE. Other risk factors includes a history o heed injury, clinical depression, and high blood pressure. The disease process is largely associated wi amyloid plaques, neurofibrillary tangles, and loss o neuronal connections i the brain. A probable diagnosis is based on the history o the illness and cognitive testing wiv medical imaging and bluid tests te rule oot other possible causes. Initial symptoms is often mistyen for normal brain agein. The examination o brain tissue is needed for a definite diagnosis, but this can nobbut tyek place efter deeth. Good nutrition, physical activity, and engagin socially are knawn te be o benefit generally in agein, and these may help in reducin the risk o cognitive decline and Alzheimer's; in 2019 clinical trials wes underway te luik at these possibilities. There's ne medications or supplements that hes been shown te decrease the risk.

Ne treatments stops or revarses its progression, though some might temporarily improve symptoms. Affected people increasingly relies on others for assistance, often placin a burden on the caregiver. The pressures can include social, psychological, physical, and economic elements. Exercise programs may be beneficial with respect to activities of daily living and can potentially improve outcomes. Behavioral problems or psychosis due te dementia is often treated wi antipsychotics, but this is nut usually recommended, as there is little benefit and an increased risk of early deeth.

As o 2020, there wes approximately 50 million people worldwide wi Alzheimer's disease. It myest often begins i people ower 65 year awd, though up te 10% of cases is early-onset affectin them i their 30s te mid-60s. It affects aboot 6% o people 65 years and awder, and women mair often nor men. The disease is named after German psychiatrist and pathologist Alois Alzheimer, whe furst described it i 1906. Alzheimer's financial burden on society is large, with an estimated global annual cost of US$1trillion. Alzheimer's disease is currently ranked as the seventh leading cause of death in the United States.